Algorithm-based prediction of HIV-1 subtype D coreceptor use.
نویسندگان
چکیده
We compared the coreceptor tropism-predicting performance of a specific genotypic algorithm for HIV-1 subtype D and that of the geno2pheno algorithm with different cutoffs. The D-specific algorithm and geno2pheno with a false-positivity rate cutoff of 2.5% had the same concordance with the phenotypic determination. The geno2pheno algorithm with a false-positivity rate cutoff of 2.5%, more sensitive but slightly less specific, seems to be an appropriate alternative.
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عنوان ژورنال:
- Journal of clinical microbiology
دوره 51 9 شماره
صفحات -
تاریخ انتشار 2013